BioInno

Tempus Fugit

In northern hemispheres, October heralds the onset of autumn and we are reminded that its cool breezes will soon blow wintry as 1996 draws to a close. Tempus fugit! The swift passage of time also reminds us that the first volume of The Oncologist will soon conclude with its sixth issue in December.

However, before 1996 becomes history, let’s pause and reflect on the pledges we made to our readership at the beginning of the year. The Founding Editors conceived the Journal to provide authoritative, topical, innovative articles in an attractive format for a very special reader: the busy, practicing physician who cares for cancer patients.

STA-21

B6175-1 1 mg
EUR 201.6
Description: JAK/STAT Signaling|STAT

STA-21

B6175-5 5 mg
EUR 1299.6
Description: IC50: 12.2 ?M for DU145 cellsSTA-21 is a STAT3 inhibitor.STAT-3, a transcription factor encoded by the STAT-3 gene, exists in a latent form in the cytoplasm.

STA-21

MBS3841236-1mg 1mg
EUR 210

STA-21

MBS3841236-2mg 2mg
EUR 310

STA-21

MBS3841236-5mg 5mg
EUR 580

STA-21

MBS3841236-5x5mg 5x5mg
EUR 2600

STA 2

MBS5784211-5mg 5(mg
EUR 915

STA 2

MBS5784211-5x5mg 5x5(mg
EUR 3970

STA 2

T34710-10mg 10mg Ask for price
Description: STA 2

STA 2

T34710-1g 1g Ask for price
Description: STA 2

STA 2

T34710-1mg 1mg Ask for price
Description: STA 2

STA 2

T34710-50mg 50mg Ask for price
Description: STA 2

STA 2

T34710-5mg 5mg Ask for price
Description: STA 2

sta Antibody

CSB-PA604967XA01DMO-02mg 0.2mg Ask for price
Description: Recombinant Drosophila teissieri (Fruit fly) sta protein

sta Antibody

CSB-PA604967XA01DMO-10mg 10mg Ask for price
Description: Recombinant Drosophila teissieri (Fruit fly) sta protein

sta Antibody

CSB-PA606360XA01DMJ-02mg 0.2mg Ask for price
Description: Recombinant Drosophila simulans (Fruit fly) sta protein

sta Antibody

CSB-PA606360XA01DMJ-10mg 10mg Ask for price
Description: Recombinant Drosophila simulans (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DKY-02mg 0.2mg Ask for price
Description: Recombinant Drosophila ananassae (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DKY-10mg 10mg Ask for price
Description: Recombinant Drosophila ananassae (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DLK-02mg 0.2mg Ask for price
Description: Recombinant Drosophila erecta (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DLK-10mg 10mg Ask for price
Description: Recombinant Drosophila erecta (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DLU-02mg 0.2mg Ask for price
Description: Recombinant Drosophila melanogaster (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DLU-10mg 10mg Ask for price
Description: Recombinant Drosophila melanogaster (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DMG-02mg 0.2mg Ask for price
Description: Recombinant Drosophila sechellia (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DMG-10mg 10mg Ask for price
Description: Recombinant Drosophila sechellia (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DMR-02mg 0.2mg Ask for price
Description: Recombinant Drosophila yakuba (Fruit fly) sta protein

sta Antibody

CSB-PA020485XA01DMR-10mg 10mg Ask for price
Description: Recombinant Drosophila yakuba (Fruit fly) sta protein

STA Macrobeads

MB-4701-2 1 Each Ask for price
Description: STA Macrobeads . With the exception of Diagnostic Microbiology Products all biochemicals described are for research use only. The biochemical reagents are not designed for use in therapeutic or diagnostic applications. We are unable to ship to individuals. Please place all orders through an established firm or institution. Nothing disclosed is to be construed as a recommendation to use our products in violation of any patents. All research products are offered without warranty or guarantee, since the ultimate condition of use and the variability in material handling are beyond our control.

Ganetespib (STA-9090)

A4385-10 10 mg
EUR 108
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

A4385-200 200 mg
EUR 800
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

A4385-5 5 mg
EUR 76
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

A4385-5.1 10 mM (in 1mL DMSO)
EUR 76
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

A4385-50 50 mg
EUR 167.2
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

A4385-S Evaluation Sample
EUR 24
Description: Metabolism|HSP#Proteases|HSP

Elesclomol (STA-4783)

A4386-10 10 mg
EUR 79.2
Description: Metabolism|HSP#Proteases|HSP

Elesclomol (STA-4783)

A4386-200 200 mg
EUR 448
Description: Metabolism|HSP#Proteases|HSP

Elesclomol (STA-4783)

A4386-5 5 mg
EUR 52.8
Description: Metabolism|HSP#Proteases|HSP

Elesclomol (STA-4783)

A4386-5.1 10 mM (in 1mL DMSO)
EUR 64
Description: Metabolism|HSP#Proteases|HSP

Elesclomol (STA-4783)

A4386-50 50 mg
EUR 176
Description: Metabolism|HSP#Proteases|HSP

Ganetespib (STA-9090)

9459-25 each
EUR 705.6

Ganetespib (STA-9090)

9459-5 each
EUR 222

Elesclomol (STA-4783)

27748-1 5 mg
EUR 180
Description: Elesclomol is a HSP-90 Inhibitor with pro-apoptotic and potential antineoplastic activities. Elesclomol induces oxidative stress and triggers mitochondrial-induced apoptosis in cancer cells.

Elesclomol (STA-4783)

27748-2 10 mg
EUR 290
Description: Elesclomol induces oxidative stress and triggers mitochondrial-induced apoptosis in cancer cells.

Ganetespib (STA-9090)

27750-2 10 mg
EUR 280
Description: Ganetespib (also known as STA-9090) is a potent small-molecule inhibitor of heat shock protein 90 (IC50=4 nM). It binds to the ATP pocket in the N-terminus of Hsp90, resulting in down-regulation of Hsp90 client protein levels. Being structurally unrelated to geldanamycin-derived Hsp90 inhibitors (17-AAG, 17-DMAG, and IPI-504), ganetespib has a unique triazolone-containing chemical structure and stands out other Hsp90 inhibitors in terms of potency, antitumor activity, and safety profile.

Ganetespib (STA-9090)

202703 5.0mg
EUR 150

Elesclomol (STA-4783)

B1815-25 each
EUR 764.4

Elesclomol (STA-4783)

B1815-5 each
EUR 235.2

Elesclomol (STA-4783)

MBS386217-100mg 100mg
EUR 1150

Elesclomol (STA-4783)

MBS386217-10mg 10mg
EUR 240

Elesclomol (STA-4783)

MBS386217-50mg 50mg
EUR 750

Elesclomol (STA-4783)

MBS386217-5mg 5mg
EUR 190

Elesclomol (STA-4783)

MBS386217-5x100mg 5x100mg
EUR 5175

Ganetespib (STA-9090)

MBS386218-100mg 100mg
EUR 360

Ganetespib (STA-9090)

MBS386218-10mg 10mg
EUR 190

Ganetespib (STA-9090)

MBS386218-50mg 50mg
EUR 260

Ganetespib (STA-9090)

MBS386218-5mg 5mg
EUR 160

Ganetespib (STA-9090)

MBS386218-5x100mg 5x100mg
EUR 1600

Elesclomol (STA-4783)

MBS578735-100mg 100mg
EUR 320

Elesclomol (STA-4783)

MBS578735-10mg 10mg
EUR 165

Elesclomol (STA-4783)

MBS578735-50mg 50mg
EUR 230

Elesclomol (STA-4783)

MBS578735-5mg 5mg
EUR 145

Elesclomol (STA-4783)

MBS578735-5x100mg 5x100mg
EUR 1290

Ganetespib (STA-9090)

MBS577870-10mg 10mg
EUR 170

Ganetespib (STA-9090)

MBS577870-25mg 25mg
EUR 180

Ganetespib (STA-9090)

MBS577870-2mg 2mg
EUR 135

Ganetespib (STA-9090)

MBS577870-50mg 50mg
EUR 225

Ganetespib (STA-9090)

MBS577870-5mg 5mg
EUR 150

Ganetespib (STA 9090)

MBS132414-100mg 100mg
EUR 1065

Ganetespib (STA 9090)

MBS132414-500mg 500mg
EUR 2775

sta-1 Antibody

CSB-PA863098XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans sta-1 protein

sta-1 Antibody

CSB-PA863098XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans sta-1 protein

sta-2 Antibody

CSB-PA631335XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans sta-2 protein

sta-2 Antibody

CSB-PA631335XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans sta-2 protein

StA-IFN-1

MBS5798889-25mg 25(mg
EUR 1155

StA-IFN-1

MBS5798889-5x25mg 5x25(mg
EUR 5040

StA-IFN-1

T38158-10mg 10mg Ask for price
Description: StA-IFN-1

StA-IFN-1

T38158-1g 1g Ask for price
Description: StA-IFN-1

StA-IFN-1

T38158-1mg 1mg Ask for price
Description: StA-IFN-1

StA-IFN-1

T38158-50mg 50mg Ask for price
Description: StA-IFN-1

StA-IFN-1

T38158-5mg 5mg Ask for price
Description: StA-IFN-1

Solanum tuberosum (STA, potato)

MBS613204-1mL 1mL
EUR 425

Solanum tuberosum (STA, potato)

MBS613204-5x1mL 5x1mL
EUR 1765

Solanum tuberosum (STA, Potato)

MBS655995-5mg 5mg
EUR 590

Solanum tuberosum (STA, Potato)

MBS655995-5x5mg 5x5mg
EUR 2500

PHA-408

527694 5.0mg
EUR 270

RTA 408

B2860-25 each
EUR 652.8

RTA 408

B2860-5 each
EUR 210

PHA 408

HY-14180 10 mg
EUR 378.79
Description: PHA 408 (PHA-408) is a potent, selective and orally active IκB kinase-2 (IKK-2) inhibitor. PHA 408 is a powerful anti-inflammatory agent against lipopolysaccharide (LPS)- and cigarette smoke (CS)-mediated lung inflammation[1].

RTA-408

MBS3602031-50mg 50mg
EUR 490

RTA-408

MBS3602031-5x50mg 5x50mg
EUR 1880

RTA-408

MBS3840358-10mg 10mg
EUR 225

RTA-408

MBS3840358-25mg 25mg
EUR 310

RTA-408

MBS3840358-5mg 5mg
EUR 190

RTA-408

MBS3840358-5x25mg 5x25mg
EUR 1380

PHA 408

MBS387618-10mg 10mg
EUR 310

PHA 408

MBS387618-25mg 25mg
EUR 580

PHA 408

MBS387618-50mg 50mg
EUR 925

PHA 408

MBS387618-5mg 5mg
EUR 210

PHA 408

MBS387618-5x50mg 5x50mg
EUR 4160

PHA-408

MBS5774377-5mg 5(mg
EUR 915

PHA-408

MBS5774377-5x5mg 5x5(mg
EUR 3970

PHA-408

T24629-10mg 10mg Ask for price
Description: PHA-408

PHA-408

T24629-1g 1g Ask for price
Description: PHA-408

PHA-408

T24629-1mg 1mg Ask for price
Description: PHA-408

PHA-408

T24629-50mg 50mg Ask for price
Description: PHA-408

PHA-408

T24629-5mg 5mg Ask for price
Description: PHA-408

RTA 408

R700990 1mg
EUR 345
Description: 1474034-05-3

Recombinant Streptothricin acetyltransferase (sta)

MBS1133897-005mgBaculovirus 0.05mg(Baculovirus)
EUR 1030

Recombinant Streptothricin acetyltransferase (sta)

MBS1133897-005mgEColi 0.05mg(E-Coli)
EUR 705

Recombinant Streptothricin acetyltransferase (sta)

MBS1133897-005mgYeast 0.05mg(Yeast)
EUR 860

Recombinant Streptothricin acetyltransferase (sta)

MBS1133897-02mgEColi 0.2mg(E-Coli)
EUR 915

Recombinant Streptothricin acetyltransferase (sta)

MBS1133897-05mgEColi 0.5mg(E-Coli)
EUR 1005

Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

I247390 25mg
EUR 27000
Description: 98092-14-9

Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

H-5435.0001 1.0mg
EUR 428.4
Description: Sum Formula: C39H65N5O9; CAS# [98092-14-9]

Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

H-5435.0005 5.0mg
EUR 1603.2
Description: Sum Formula: C39H65N5O9; CAS# [98092-14-9]

Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

TRC-I247390-25MG 25 mg Ask for price

EMD (Emerin, STA, EDMD) (PE)

MBS6157627-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) (PE)

MBS6157627-5x01mL 5x0.1mL
EUR 3800

EMD, CT (Emerin, STA, EDMD)

MBS649006-02mL 0.2mL
EUR 695

EMD, CT (Emerin, STA, EDMD)

MBS649006-5x02mL 5x0.2mL
EUR 2975

EMD (Emerin, STA, EDMD) (AP)

MBS6131112-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) (AP)

MBS6131112-5x01mL 5x0.1mL
EUR 3800

EMD (Emerin, STA, EDMD) APC

MBS6136415-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) APC

MBS6136415-5x01mL 5x0.1mL
EUR 3800

EMD (Emerin, STA, EDMD) (HRP)

MBS6152324-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) (HRP)

MBS6152324-5x01mL 5x0.1mL
EUR 3800

EMD (Emerin, STA, EDMD) (FITC)

MBS6147021-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) (FITC)

MBS6147021-5x01mL 5x0.1mL
EUR 3800

Human STA-IgM ELISA Kit

MBS3801995-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human STA-IgM ELISA Kit

MBS3801995-48StripWells 48-Strip-Wells
EUR 550

Human STA-IgM ELISA Kit

MBS3801995-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human STA-IgM ELISA Kit

MBS3801995-96StripWells 96-Strip-Wells
EUR 765

Human STA-IgG ELISA Kit

MBS3803368-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human STA-IgG ELISA Kit

MBS3803368-48StripWells 48-Strip-Wells
EUR 550

Human STA-IgG ELISA Kit

MBS3803368-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human STA-IgG ELISA Kit

MBS3803368-96StripWells 96-Strip-Wells
EUR 765

EMD (Emerin, STA, EDMD) (Biotin)

MBS6141718-01mL 0.1(mL
EUR 875

EMD (Emerin, STA, EDMD) (Biotin)

MBS6141718-5x01mL 5x0.1mL
EUR 3800

Solanum tuberosum (STA, potato) (AP)

MBS610999-1mg 1mg
EUR 585

Solanum tuberosum (STA, potato) (AP)

MBS610999-5x1mg 5x1mg
EUR 2475

Solanum tuberosum (STA, Potato) (AP)

MBS656714-1mg 1mg
EUR 585

Solanum tuberosum (STA, Potato) (AP)

MBS656714-5x1mg 5x1mg
EUR 2475

GlycoBind Binding Buffer - STA/STL

21510914-1 -
EUR 22.88

GlycoBind Binding Buffer - STA/STL

21510914-2 -
EUR 50.5

GlycoBind Binding Buffer - STA/STL

21510914-3 -
EUR 77.36

GlycoElute Elution Buffer - STA/STL

21511311-1 -
EUR 33.57

GlycoElute Elution Buffer - STA/STL

21511311-2 -
EUR 54.91

GlycoElute Elution Buffer - STA/STL

21511311-3 -
EUR 79.47

Solanum tuberosum (STA, Potato) (FITC)

MBS656550-2mg 2mg
EUR 510

Solanum tuberosum (STA, Potato) (FITC)

MBS656550-5x2mg 5x2mg
EUR 2135

Crude Solanum tuberosum (Potato) -STA-

L-4700-100 100 mg Ask for price
Description: Crude Solanum tuberosum (Potato) -STA-, 100mg Product volume may vary. With the exception of Diagnostic Microbiology Products all biochemicals described are for research use only. The biochemical reagents are not designed for use in therapeutic or diagnostic applications. We are unable to ship to individuals. Please place all orders through an established firm or institution. Nothing disclosed is to be construed as a recommendation to use our products in violation of any patents. All research products are offered without warranty or guarantee, since the ultimate condition of use and the variability in material handling are beyond our control.

Solanum tuberosum (STA, Potato) (Biotin)

MBS656164-2mg 2mg
EUR 530

Solanum tuberosum (STA, Potato) (Biotin)

MBS656164-5x2mg 5x2mg
EUR 2230

Pepstatin, acetylated [Ac-Val-Val-Sta-Ala-Sta]

MBS658864-1mg 1mg
EUR 750

Pepstatin, acetylated [Ac-Val-Val-Sta-Ala-Sta]

MBS658864-5x1mg 5x1mg
EUR 3235

MagSi-STA 1.0

MD01001 2 mL
EUR 426

MagSi-STA 1.0

MD03001 10 mL
EUR 1434

MagSi-STA 1.0

MD04001 100 mL
EUR 7158

MagSi-STA 600

MD16001 2 mL
EUR 470.4

MagSi-STA 600

MD18001 10 mL
EUR 1572

MagSi-STA 600

MD19001 100 mL
EUR 9060

Omaveloxolone (RTA-408)

B3576-25 25 mg
EUR 332
Description: Apoptosis|KEAP1-Nrf2

Omaveloxolone (RTA-408)

B3576-5 5 mg
EUR 108
Description: Apoptosis|KEAP1-Nrf2

RTA 408-d3

R700992 50mg
EUR 9200

RTA 408-d3

TRC-R700992-50MG 50 mg Ask for price

EMD, CT (Emerin, STA, EDMD) (AP)

MBS6473772-02mL 0.2mL
EUR 980

Our commitment is to critically review and publish papers designed to interpret the vast amounts of data available to physicians. As the famed radiotherapist and Founding Editor, Eli Glatstein, summarized, “The Oncologist emphasizes the interpretation rather than the data.” The Oncologist to date has published more than forty manuscripts from international authorities. The inaugural issue featured, among other highly acclaimed papers, “Locally Advanced Breast Cancer,” by Valero, Buzdar and Hortobagyi, and David Kuter’s “Thrombopoietin:

Biology and Clinical Applications.” Fidias, Chabner and Grossbard contributed “Purine Analogs for the Treatment of Low-Grade Lymphoproliferative Disorders” in the next issue, and Pavletic and Armitage proffered an update on “Bone Marrow Transplantation for Cancer.” Issue 4 highlighted Jemi Olak and Arthur Ng’s “Diagnosis and Management of Early-Stage Non-Small Cell Lung Cancer,” as well as “Multimodality Therapy for Esophageal Cancer” by Siewert, Stein and Fink. In this current issue, “Dose Intensity of Chemotherapy for Childhood Cancers,” by Smith, Abrams, Trimble and Ungerleider, and “Surgical Sphincter Preservation in Rectal Cancer” by Peter M.

Schlag present contemporary and authoritative views of two important clinical topics which also document the Journal’s intent to discuss both adult and pediatric cancer care. Our Meet The Professor section is fast becoming a popular feature which attracts comments from readers and responses from the author professor.

We call your attention to Professor Barrie R. Cassileth’s fascinating article, “Alternative and Complementary Cancer Treatments,” and her commentary in this issue.

The Physician Education section has presented hematopoiesis through informative and beautifully illustrated papers with texts by distinguished hematologists and molecular biologists. In this issue, we feature the first Patient Care section, From The Bethesda Post, wherein clinical trials and experimental treatments are announced. In cooperation with The Cancer Letter, The Oncologist News Bulletin presents late-breaking news pertinent to the world’s cancer care community.

With this issue, we have instituted an addition to this section, featuring information from Memorial Sloan-Kettering Cancer Center on a study involving Ashkenazi Jewish women. We urge cancer centers, pharmaceutical and biotechnology companies to avail themselves of this section by sending our editorial office your newsworthy reports. We hope that our readers are benefiting from the Journal and enjoying the art which has graced it. In order to assess how well we are fulfilling our pledges to our readership, we need to hear from you.

Tell us how we can make The Oncologist more relevant to your medical practice. We promise to share your comments with our Editorial Board to further enhance the Journal. In so doing, we will draw closer to fulfilling our pledge to you, our readers.

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